Research Background: PhD and initial post-doctoral research on the use of NMR to study biological molecules and their interactions. Subsequent diverse experience in the pharmaceutical industry (GSK) applying solid state and liquid state NMR and MRI to drug polymorphism, drug receptor characterization, and drug action in biological models of disease.
Research Interests
Current interests focus on solid state NMR to characterize biomaterial structure using cell culture methods and isotope labelling, but also including drug product and timber product characterization.
Teaching
Supporting undergraduate and postgraduate research projects.
Publications
Solid state NMR - An indispensable tool in organic-inorganic biocomposite characterization; refining the structure of octacalcium phosphate composites with the linear metabolic di-acids succinate and adipate
Solid State Nucl Magn Reson
(2018)
95
1
(doi: 10.1016/j.ssnmr.2018.08.004)
Essential but sparse collagen hydroxylysyl post-translational modifications detected by DNP NMR
Chemical Communications
(2018)
54
12570
(doi: 10.1039/C8CC04960B)
In situcharacterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR
Chemical communications (Cambridge, England)
(2017)
53
13316
(doi: 10.1039/c7cc06624d)
Solid state NMR of salivary calculi: Proline-rich salivary proteins, citrate, polysaccharides, lipids, and organic–mineral interactions
Comptes Rendus Chimie
(2016)
19
1665
(doi: 10.1016/j.crci.2015.07.001)
Solid state NMR of isotope labelled murine fur: a powerful tool to study atomic level keratin structure and treatment effects.
J Biomol NMR
(2016)
66
93
(doi: 10.1007/s10858-016-0056-7)
Nuclear magnetic resonance spectroscopy fingerprinting of tissues allows detailed analysis of glycation reactions
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
(2016)
97
A7
Rationalization of the Color Properties of Fluorescein in the Solid State: A Combined Computational and Experimental Study
Chemistry (Weinheim an der Bergstrasse, Germany)
(2016)
22
10065
(doi: 10.1002/chem.201601340)
Tuning hardness in calcite by incorporation of amino acids.
Nat Mater
(2016)
15
903
(doi: 10.1038/NMAT4631)
Connecting defects and amorphization in UiO-66 and MIL-140 metal–organic frameworks: a combined experimental and computational study.
Physical chemistry chemical physics : PCCP
(2016)
18
2192
(doi: 10.1039/c5cp06798g)
Preparation of highly and generally enriched mammalian tissues for solid state NMR.
J Biomol NMR
(2015)
63
119
(doi: 10.1007/s10858-015-9977-9)
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