Dr David Reid

Research Background: PhD and initial post-doctoral research on the use of NMR to study biological molecules and their interactions. Subsequent diverse experience in the pharmaceutical industry (GSK) applying solid state and liquid state NMR and MRI to drug polymorphism, drug receptor characterization, and drug action in biological models of disease.

Research Interests

Current interests focus on solid state NMR to characterize biomaterial structure using cell culture methods and isotope labelling, but also including drug product and timber product characterization.

Teaching

Supporting undergraduate and postgraduate research projects.

Publications

2P-0535 Short term remodelling of the aorta of cholesterol fed New Zealand White (NZW) rabbits shown by high-resolution magnetic resonance imaging (MRI)

L Hegyi, AL Busza, PD Hockings, JN Skepper, TA Carpenter, GA Whelan, DC Grimsditch, P Overend, GM Benson, DG Reid, KE Suckling, PL Weissberg

Atherosclerosis Plus

(2003)

157

(doi: 10.1016/S1567-5688(03)90674-X)

CONFORMATIONS OF 2 DUPLEX FORMS OF D(TCGA) IN SLOW-EXCHANGE EQUILIBRIUM CHARACTERIZED BY NMR

DG Reid, SA Salisbury, T Brown, DH Williams

Biochemistry

(2002)

4325

(doi: 10.1021/bi00337a011)

Proton nuclear Overhauser effect study of the structure of an actinomycin D complex with a self-complementary tetranucleoside triphosphate

DG Reid, SA Salisbury, DH Williams

Biochemistry

(2002)

1377

(doi: 10.1021/bi00275a009)

Proton nuclear Overhauser effect study of the structure of a deoxyoligonucleotide duplex in aqueous solution

DG Reid, SA Salisbury, S Bellard, Z Shakked, DH Williams

Biochemistry

(2002)

2019

(doi: 10.1021/bi00277a044)

Application for proton NMR spectral editing techniques for selective observation of nitrogen-hydrogen (N-H) protons in an actinomycin D complex with a tetranucleotide duplex

DG Reid, DM Doddrell, KR Fox, SA Salisbury, DH Williams

Journal of the American Chemical Society

(2002)

105

5945

(doi: 10.1021/ja00356a054)

Preparation of recombinant tissue inhibitor of metalloproteinases‐1 (TIMP‐1) in high yield and identification of a hydrophobic surface feature

DJ Hodges, DG Reid, AD Rowan, IM Clark, TE Cawston

European journal of biochemistry

(2001)

257

562

(doi: 10.1046/j.1432-1327.1998.2570562.x)

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean.

JC Clapham, JR Arch, H Chapman, A Haynes, C Lister, GB Moore, V Piercy, SA Carter, I Lehner, SA Smith, LJ Beeley, RJ Godden, N Herrity, M Skehel, KK Changani, PD Hockings, DG Reid, SM Squires, J Hatcher, B Trail, J Latcham, S Rastan, AJ Harper, S Cadenas, JA Buckingham, MD Brand, A Abuin

Nature

(2000)

406

415

(doi: 10.1038/35019082)

Purification and secondary structural analysis of tissue inhibitor of metalloproteinases-1.

DJ Hodges, DC Lee, CJ Salter, DG Reid, GP Harper, TE Cawston

Biochimica et biophysica acta

(1994)

1208

(doi: 10.1016/0167-4838(94)90164-3)

An electrophysiological and spectroscopic study of the properties and structure of biological calcium channels. Investigations of a model ion channel

DG Reid, LK MacLachlan, CJ Salter, MJ Saunders, SD Jane, AG Lee, EJ Tremeer, SA Salisbury

Biochimica et Biophysica Acta (BBA) - Biomembranes

(1992)

1106

264

(doi: 10.1016/0005-2736(92)90005-7)

A N-15 NUCLEAR MAGNETIC-RESONANCE STUDY OF THE BIOSYNTHESIS OF QUINOXALINE ANTIBIOTICS

DG Reid, DM Doddrell, DH Williams, KR Fox

Biochimica et Biophysica Acta

(1984)

798

111

(doi: 10.1016/0304-4165(84)90017-5)

Dr David Reid

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